BRUCELLOSIS
Brucellosis anedhe sokina jenthuvulla nundi pasteurized cheyani palu ledha takuva vadina mavshani tesukovadham vallana ledha vati sarvalatho sanihitha sambhandhala valla kalige athantha antukune junosis. Dhinni andulant javram mariyu madhya dhara javram ani kuda antaru.
Vere perulu brucellosis ki undulant fever, undulating fever, Mediterranean fever, Malta fever, Cyprus fever, rock fever (Micrococcus melitensis).
Symptoms : coughing
Brucellosis jathulu chinavi, gram negative, non motile, nonspore forming, rod shaped (coccobacilli) bacteria. Evi facultative karantha ra parasaties ga panichesthai, derrga kalika vyadhi karanamu iythai , edhi sardranam ga jivethaniki konasaguthundhi. Naulugu jathalu manavulaku sokuthai : B. abortus, B. canis, B. melitensis, mariyu B. suis. B. abortus anadhe athi thakuva virulent kante B. melitensis mariyu adhi primarily disease of cattle ani antaru. B. canis dogs ki kuda pakuthai. B. melitensis anedhi chala virulent mariyu invasive species. Brucellosis 20 va shathabdham prarambham nunchi janthuvulu la lo mariyu manavullaku gurthinchabadhindhi.
Signs mariyu symptoms
Lakshanalu aneka ethara javrasambandham iyna vyadhi tho samandham kaligi untai, chemataku pradhanam esthai. Vyadhi yokka vyavdhi konni vararala nundhi chala nelala kedha samvastharm varaku marchavachu.
Vyadhi yokka modati dashalo bacteremia sambavisthundhi mariyu avanchinaya jivullu, chemata (tarachu lakshanam achhu vasana konnisarlu thadiyendugaddi tho pollabaduthundhi), mariyu valasa artharalgia mariyu myalgia. Raktha parikshalu takkuva sankyalo tella raktha kanallu mariyu yerra raktha kanallu bahirangtam chesthai, aminotransferase mariyu alanine aminotransferase vanti kaliyaka enzymes yooka kontha yethuna chuputhai mariyu sanukula bengal gulabi mariyu huddleston prathicheyaranu pradarsitha.
Gastrointertinal lakshanalu 70% cases la lo sambavisthai mariyu vikaram, vomits, akalli taggadham, anukokundha baruvu taggadham, kadupu noppi, malabadakam, verechana, vistharinchina kaleyam, kalaya manta, kaleya gadda mariyu vistharinchina vanti lakshanalu untai.
E samudhyam kanisam portugal,Israel, Syria, mariyu Jordan, lo malaria jvaram ga pellustharu. Malt javram yokka samayam lo meltiococcemia (raktham lo brucellae untatu gurthu chestundhi) sadranam ga tryptose medium ledha albini medium madhayamam lo raktha samskurthi davra pradarshincha badhuthundhi. Jikestha cheyaka pothe, e vyadhi ledha derkalikam ga maruthundhi. Brucellosis yokka sadranam ga yamakula mariyu kella lo sambavisthai mariyu sacroiliitis e vadiki chala lakshalanu unai. Orchitis purshulalo kuda sadranam.
Treatment
Tetracyclines, rifampin, mariyu aminoglycosides streptomycin mariyu gentamicin vanti antibiotics burucella bacteria yaku vethirekam ga panichesthai. Yanapatiki, okati kante yekkuva antibiotic vadakam chala varalu avasaram, yenduku ante bacteria ya ku kanala lo podhigedhi.
Peddalu bangaru pramanika chekistha 14 rojulo patta streptomycin 1 gram yokka intermuscular injection nu mariyu notti doxycycline 100 gram lu rojuku rondu sarlu 45 rojulu vadali. Streptomycin andubatu lo lenappudhu ledha virudham ga unnapudhu 7 rojulo oka sari interamuscular injection davra jentamision 5 mg.visthru tham ga upayoginche maro niyamavalli doxycycline plus rojuku rondu sarlu kanisam 6 varala pattu untundhi. E niyamalavi noti paripalana yokka prayojanani kaligi undhi.
Neurobrucellosis chikistha ku ripenpin mariyu co trimosjol theraphy vijayavantam ga upayoginchabadhindhi.
Roga nirdharana
1909 lo british army mariyu navy dhalam lo malt lo unna e vyadhi maranalu 2 %. marananiki chala taruchuga karanam endocarditis. Antibiotics mariyu sathra chikistha la lo eivalla purogathu lu karanam ga maranani nivrarinchadam lo vijayavantham ayaru. Tikallu veyadham mariyu ethara pashu yadha niyntharna mandulanu pariveshinchadham lo mariyu samkaramana unnappudhu janthuvullu la nu vyadhi ni nirmalinchadham lo davra manava brucellosis nivarana sadhincha vachu. Prasthutham, manavulaku samadhvantam iyna vaccine anudu batulo ledhu. Pallanu udaka badadaniki mundhu, ledha ethara pallu uthaputhanu uttapathi cheydaniki upayoginche mundhu tesukovadham dvara prasaram cheyakunda kapaduthundhi.